Macro Trials
Macro is the partner behind your most reliable clinical trial sites
A community-physician site network for US ophthalmology clinical trials. We partner with sponsors and CROs to deliver high-performing, research-experienced ophthalmologists, activate sites in weeks, and enroll reliably in diverse communities across the United States.
Trusted By Leading Pharma Sponsors and CROs
WHAT WE DO
Macro is at the center of your next clinical trial
We work with sponsors and CROs to execute clinical trials for high-value therapeutics. We create access for diverse candidates and partner with leading clinicians looking to stay on the forefront of care.
Sponsors & CROs
A national network of proven investigators, activated quickly and managed end to end
Macro streamlines site selection, startup, and ongoing oversight to provide predictable performance, reliable timelines, and data you can trust.
Partner with Macro
Two ways to partner, whether Macro runs your whole research operation or just handles the business side.
Whether Macro runs your entire research operation or handles the business side of studies you run yourself, partnership brings deal flow, negotiated budgets, and sponsor relationships without adding overhead.
Patients
Access to leading therapies close to home.
Macro sites expand availability of advanced treatments, offer free evaluations, and maintain strong retention through coordinated support.
Our Model
Macro uses a centralized hub and spoke research model that brings consistency, speed, and quality to every study.
Hub: Centralized Operations
Handles all trial setup and infrastructure:
- Contracting, budgeting, and finance
- Regulatory coordination and IRB submissions
- Equipment procurement and protocol setup
- Standardized workflows and SOPs
- Quality oversight and training
- Vendor and IP management
- Real time monitoring of site performance
Spoke Sites: Community Based Investigators
Where enrollment and patient care happen:
- Experienced clinicians with relevant patient populations
- Embedded Macro coordinators
- Multilingual patient support
- Local access for treatment naive and hard to reach populations
This model gives sponsors the speed and consistency of a unified site while maintaining the reach of real-world community practices.
Two ways to join the Macro Site Network
Site Partners
Site Partners hand the entire research operation to Macro. We staff the coordinators, run regulatory and IRB, negotiate the budgets, and bring the studies, so your practice adds a research revenue line without adding a research department.
Alliance Partners
Alliance Partners keep their own research team and full control of their practice. Macro brings the deal flow and handles the business side: sponsor relationships, budget negotiation, and contracting.
Many Alliance Partners expand into full Site Partner relationships as their research volume grows.
What Sets Macro Apart
Deep expertise in high value therapeutic areas
Our investigators have extensive experience across the full spectrum of the eye: retina, glaucoma, cornea, dry eye, and thyroid eye disease, including complex biologics, devices, and interventional protocols.
Fast activation and disciplined operational delivery
Macro’s centralized contracting, regulatory, and logistics model shortens startup timelines and ensures every site begins with the right equipment, staff, and workflow in place.
Reliable enrollment and strong retention
Our embedded coordinators and community-based clinicians reach patients who are often missed by traditional sites. Macro sites consistently achieve or exceed enrollment targets and can reach treatment-naïve patient populations through our national footprint.
Access to diverse real world patient populations
Macro’s partners reach communities with broad demographic representation. We support the inclusion of underrepresented patients across our ophthalmology studies.
End to end site support that removes burden from investigators
Macro manages budgeting, contracting, equipment procurement, IRB coordination, coordinator staffing, and visit logistics. Clinicians focus on oversight and care, while Macro ensures quality and compliance.
Study ready infrastructure that supports consistent high-quality data
Central oversight, experienced coordinators, and standardized workflows enable clean data collection and near perfect protocol adherence across studies.
Accelerating Trial Execution
Macro delivers consistent, high-performing site operations across the full spectrum of ophthalmology, from anterior segment through retina. Our embedded coordinators, experienced investigators, and centralized oversight create a site network that activates quickly, enrolls reliably, and generates high-quality data across study phases and designs.